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FDA Notice Calls CBD "Beneficial" Last Updated on 2017-08-23 19:35:25 Cannabis Business Times | August 21st 2017 | Melissa Schiller In an Aug. 14 notice requesting public comments for a UN drug committee, the U.S. Food and Drug Administration (FDA) said CBD was the only beneficial substance on the international committee’s list of 17 substances under review. In the descriptions of the substances under review, the FDA stated, “CBD has been shown to be beneficial in experimental models of several neurological disorders, including those of seizure and epilepsy. In the United States, CBD-containing products are in human clinical testing in three therapeutic areas, but no such products are approved by FDA for marketing for medical purposes in the United States.” The notice goes on to say that CBD is a Schedule I controlled substance under the Controlled Substances Act (CSA). The FDA is looking for public input on CBD’s (and the... More »
How CBD Changes The Brain To Treat Psychiatric Disorders Last Updated on 2017-07-25 11:56:36 Canna Tech |  July 25, 2017  |  By Jack Woodhouse In a recent study, published in Frontiers in Pharmacology, a group of scientists from the University of São Paulo in Brazil reviewed all the available research in order to learn more about the mechanisms at play when psychiatric disorders are treated with CBD. The study suggests that CBD’s therapeutic effects are caused by a number of acute mechanisms as well as changes in the structure of the brain over time, known as neuroplasticity. CBD has been proven to offer a broad spectrum of therapeutic actions, which include anxiolytic, antipsychotic, antidepressant, anticonvulsant, and neuroprotective effects. These have been studied over a large range of psychiatric and neurodegenerative disorders. Although most of these putative therapeutic properties were initially described in animal models, clinical... More »
A powerful new form of medical marijuana, without the high Last Updated on 2017-07-24 16:21:23 The Washington Post  |  December 31, 2016  |  By David Kohn ... in the past 10 years, scientists have concluded that CBD may be quite useful.  Dozens of studies have found evidence that the compound can treat epilepsy as well as a range of other illnesses, including anxiety, schizophrenia, heart disease and cancer ...   Source: https://www.washingtonpost.com/national/health-science/a-powerful-new-form-of-medical-marijuana-without-the-high/2016/12/29/81bbf7c0-b5b2-11e6-b8df-600bd9d38a02_story.html?utm_term=.3e5b037cbf41 More »
Effects of Cannabidiol in Psychiatric Disorders - Anxiety & Depression Last Updated on 2017-07-24 13:11:17 Campos AC1, Fogaça MV1, Scarante FF1, Joca SRL2, Sales AJ2, Gomes FV3, Sonego AB1, Rodrigues NS1, Galve-Roperh I4,5, Guimarães FS1.   Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric disorders, including anxiety, psychosis, and depression. The mechanisms responsible for these effects, however, are still poorly understood. Similar to clinical antidepressant or atypical antipsychotic drugs, recent findings clearly indicate that CBD, either acutely or repeatedly administered, induces plastic changes. For example, CBD attenuates the decrease in hippocampal neurogenesis and dendrite spines density induced by chronic stress and prevents microglia activation and the decrease in the number of parvalbumin-positive GABA neurons in a pharmacological model of schizophrenia. More recently, it was found that CBD modulates cell... More »
Cannabidiol in Psychiatric Disorders Last Updated on 2017-07-18 19:13:08 Medical Abstract 2017 May 23;8:269. doi: 10.3389/fphar.2017.00269. eCollection 2017. Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders. Campos AC1, Fogaça MV1, Scarante FF1, Joca SRL2, Sales AJ2, Gomes FV3, Sonego AB1, Rodrigues NS1, Galve-Roperh I4,5, Guimarães FS1. Author information Abstract Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric disorders, including anxiety, psychosis, and depression. The mechanisms responsible for these effects, however, are still poorly understood. Similar to clinical antidepressant or atypical antipsychotic drugs, recent findings clearly indicate that CBD, either acutely or repeatedly administered, induces plastic changes. For example, CBD attenuates the decrease in hippocampal neurogenesis and dendrite spines density induced... More »